Evolution of a malaria resistance gene in wild primates
Evolution of a malaria resistance gene in wild primates Nature advance online publication 24 June 2009. doi:10.1038/nature08149 Authors: Jenny Tung, Alexander Primus, Andrew J. Bouley, Tonya F. Severson, Susan C. Alberts & Gregory A. Wray The ecology, behaviour and genetics of our closest living relatives, the nonhuman primates, should help us to understand the evolution of our own lineage. Although a large amount of data has been amassed on primate ecology and behaviour, much less is known about the functional and evolutionary genetic aspects of primate biology, especially in wild primates. As a result, even in well-studied populations in which nongenetic factors that influence adaptively important characteristics have been identified, we have almost no understanding of the underlying genetic basis for such traits. Here, we report on the functional consequences of genetic variation at the malaria-related FY (DARC) gene in a…
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Evolution of a malaria resistance gene in wild primates
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